Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004453 | 0.85 | SNCA (0.36) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL21147289 | 0.85 | PIK3CA (0.38) | — | |
| SCHEMBL21147086 | 0.85 | GRM5 (0.41) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL22537807 | 0.81 | ACACB (0.34) | — | |
| SCHEMBL20005163 | 0.79 | MAPT (0.44) | — | |
| SCHEMBL20005161 | 0.78 | GRM5 (0.36) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL22537832 | 0.78 | PIK3CA (0.36) | — | |
| SCHEMBL20005146 | 0.77 | SNCA (0.36) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL21147267 | 0.75 | SNCA (0.51) | — | |
| SCHEMBL22537854 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |