SCHEMBL20005189

SCHEMBL20005189

CCCCOc1cc(C)c(C#Cc2ccc3cc(OC)ccc3c2)cc1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.37
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ACACB O00763 7/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
PPARG P37231 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PDE2A O00408 1/20 0.34
PDE10A Q9Y233 1/20 0.34
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19999370 0.81 ACACB (0.40) ACACBNPC1RAB9A
SCHEMBL20004816 0.81 S1PR1 (0.36) LMNATSHRACACB
SCHEMBL20005235 0.81 S1PR1 (0.36) LMNATSHRACACB
SCHEMBL9743365 0.79 AHR (0.53) AHRLMNAHTTTSHRSMN1; SMN2
SCHEMBL20005204 0.76 ACACB (0.42) HTTACACB
SCHEMBL9744024 0.76 AHR (0.50) AHRLMNAHTTTSHRSMN1; SMN2
SCHEMBL9742623 0.75 MCHR1 (0.56) AHRLMNAHTTTSHRSMN1; SMN2
SCHEMBL9742615 0.75 AHR (0.49) AHRLMNAHTTTSHRSMN1; SMN2
SCHEMBL9742363 0.75 AHR (0.49) AHRLMNAHTTTSHRSMN1; SMN2
SCHEMBL20004874 0.75 RARB (0.36) ACACBMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed