Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450712 | 1.00 | TDP1 (0.36) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL14217635 | 0.84 | TDP1 (0.32) | TDP1LMNAL3MBTL1 | |
| SCHEMBL13621719 | 0.84 | TDP1 (0.32) | TDP1 | |
| SCHEMBL9915203 | 0.82 | TDP1 (0.31) | TDP1 | |
| SCHEMBL14845686 | 0.82 | TDP1 (0.38) | TDP1TSHR | |
| SCHEMBL18089526 | 0.82 | TDP1 (0.38) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL20172545 | 0.82 | TDP1 (0.38) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL14294311 | 0.82 | TDP1 (0.38) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL18016628 | 0.82 | TDP1 (0.38) | TDP1TSHR | |
| SCHEMBL15357334 | 0.82 | TDP1 (0.38) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054959-A1 | COMPOUNDS FOR TREATMENT OF LIPOPROTEIN METABOLISM DISORDERS | AARHUS UNIVERSITET (DK) | 2018-03-29 | — | — | WO | disclosed |