Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294311 | 1.00 | TDP1 (0.38) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL14478517 | 0.85 | LMNA (0.46) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL11947749 | 0.85 | LMNA (0.46) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL20172545 | 0.84 | TDP1 (0.38) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL8766931 | 0.83 | LMNA (0.44) | TDP1LMNAL3MBTL1KDM4E | |
| SCHEMBL15450712 | 0.82 | TDP1 (0.36) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL20005538 | 0.82 | TDP1 (0.36) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL14469398 | 0.81 | TDP1 (0.40) | TDP1TSHR | |
| SCHEMBL18653753 | 0.81 | TDP1 (0.40) | TDP1TSHR | |
| SCHEMBL14839145 | 0.80 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016148674-A1 | CONJUGATES FOR TREATING DISEASES | ENDOCYTE, INC. (US) | 2016-09-22 | — | — | WO | disclosed |