SCHEMBL2000571

SCHEMBL2000571

[O]c1ccn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3068150 0.67 SCN4A (0.62)
Ammonia Solution, Strong SCHEMBL27788006 0.67 USP2 (0.41)
SCHEMBL1456892 0.65 HCAR2 (0.41)
Ammonia Solution, Strong SCHEMBL27321084 0.64 HCAR2 (0.40)
SCHEMBL255580 0.63
Ammonia Solution, Strong SCHEMBL27731899 0.63
SCHEMBL27496110 0.63 HCAR2 (0.70)
SCHEMBL28185300 0.63
SCHEMBL157023 0.62
SCHEMBL403109 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130427-A PYRAZOLES AGFA-GEVAERT, N.V. (BE) 1978-12-19 US claimed
WO-2023112856-A1 FUSED HETEROCYCLIC DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT クミアイ化学工業株式会社 2023-06-22 WO disclosed
EP-3444238-B1 PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS SATO PHARMA (JP) 2021-12-08 EP disclosed
EP-3444238-A2 PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS Sato Pharmaceutical Co., Ltd. (JP) 2019-02-20 EP disclosed
CN-109096194-A A kind of Biguanide derivative, pharmaceutical composition, preparation method and purposes 湖南师范大学 2018-12-28 CN disclosed
EP-2878594-B1 DIFLUOROMETHYLENE COMPOUND SATO PHARMA (JP) 2018-11-28 EP disclosed
EP-2927218-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9650380-B2 Difluoromethylene compound SATO PHARMACEUTICAL CO., LTD. (JP) 2017-05-16 US disclosed
US-20170044158-A1 DIFLUOROMETHYLENE COMPOUND SATO PHARMACEUTICAL CO., LTD. (JP) 2017-02-16 US disclosed
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5066574-A Hydantoin derivatives KONICA CORPORATION (JP) 1991-11-19 US disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0422513-A2 A silver halide photographic light-sensitive material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-04-17 EP disclosed
US-4994571-A Reacting heterocycle-containing sulfonamide compound with carbonyl compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-19 US disclosed
US-4992360-A Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-02-12 US disclosed
EP-0305939-A1 Process of producing sulfonylurea derivatives Takeda Chemical Industries, Ltd. (JP) 1989-03-08 EP disclosed
EP-0267491-A2 Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1988-05-18 EP disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed
US-4130427-A PYRAZOLES AGFA-GEVAERT, N.V. (BE) 1978-12-19 US disclosed