SCHEMBL403109

SCHEMBL403109

Clc1ccn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392004 0.67
SCHEMBL3068150 0.67 SCN4A (0.62)
SCHEMBL11707071 0.66
SCHEMBL482367 0.64 POLB (1.00)
SCHEMBL2003550 0.64
SCHEMBL84834 0.63
SCHEMBL3264763 0.63
SCHEMBL21741426 0.63
SCHEMBL193779 0.63
SCHEMBL3722291 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478107-B Preparation method of energetic material precursor compound 北京理工大学 2025-05-16 CN claimed
CN-116478107-A Preparation method of energetic material precursor compound 北京理工大学 2023-07-25 CN claimed
CN-108148068-B Pyrazolo [1,5-a ] pyridine drug molecule with antitumor activity and preparation method and application thereof 河南科技大学第一附属医院 2020-09-15 CN claimed
CN-109608464-A A kind of radioiodination Larotrectinib compound and its preparation method and application 上海健康医学院 2019-04-12 CN claimed
CN-107235903-A A kind of preparation method of pyrazole compound 长沙深橙生物科技有限公司 2017-10-10 CN claimed
CN-106883177-A A kind of preparation method of benzene substituted pyrazole derivative 长沙深橙生物科技有限公司 2017-06-23 CN claimed
CN-102791714-B N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as PDE10A inhibitors HOFFMANN LA ROCHE 2015-03-25 CN claimed
CN-103429590-A 1,4 thiazepine/sulfone as BACE1 and/or BACE2 inhibitors HOFFMANN LA ROCHE 2013-12-04 CN claimed
CN-101691356-A Method for synthesizing Baylis-Hillman addition compound containing 5-chloropyrazolo rings UNIV ZHEJIANG TECHNOLOGY 2010-04-07 CN claimed
EP-0174798-A1 Process for preparing a pyrazole herbicide ELI LILLY AND COMPANY (US) 1986-03-19 EP claimed
JP-6009316-A None JP disclosed
US-20250388536-A1 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS HOFFMANN-LA ROCHE INC. (US) 2025-12-25 US disclosed
EP-4644396-A1 TOLL-LIKE RECEPTOR INHIBITOR, AND PREPARATION THEREFOR AND APPLICATION THEREOF Visionpharma (Nantong) Co., Ltd (CN) 2025-11-05 EP disclosed
EP-4642782-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF Pliant Therapeutics, Inc. (US) 2025-11-05 EP disclosed
WO-2025131049-A1 DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES AND USES THEREOF IGNIS THERAPEUTICS (SUZHOU) LIMITED (CN) 2025-06-26 WO disclosed
US-4587348-A Process for preparing herbicidal 5-cyano-1-phenyl-N-methyl-1H-pyrazole-4-carboxamide ELI LILLY AND COMPANY (US) 1986-05-06 US disclosed
EP-0177242-A2 Pollen formation inhibiting pyrazoles ELI LILLY AND COMPANY (US) 1986-04-09 EP disclosed
EP-0174798-A1 Process for preparing a pyrazole herbicide ELI LILLY AND COMPANY (US) 1986-03-19 EP disclosed
US-4025530-A ABSCISSION OF FRUIT ABBOTT LABORATORIES (US) 1977-05-24 US disclosed
US-3932453-A PLANT GROWTH REGULATORS ABBOTT LABORATORIES (US) 1976-01-13 US disclosed