Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506745 | 0.84 | PPARA (0.43) | CA12CA1CA7CA14CTSS | |
| SCHEMBL18506647 | 0.81 | EPHX2 (0.41) | CA12CA1CA7CA14CTSS | |
| SCHEMBL10073884 | 0.75 | POLB (0.35) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL5381278 | 0.73 | PPIA (0.49) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL18506733 | 0.72 | PPARA (0.45) | CA12CA1CA7CA14CTSS | |
| SCHEMBL6167707 | 0.71 | CA12 (0.40) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL19559839 | 0.71 | ADRB2 (0.52) | CA12CA1CA7CA14CTSS | |
| SCHEMBL17691231 | 0.71 | EPHX2 (0.42) | CA12CA1CA7CA14CTSS | |
| SCHEMBL1752478 | 0.70 | MEN1 (0.37) | CA12CA1CA7CA14CTSK | |
| SCHEMBL7372 | 0.70 | AKT1 (0.46) | CA12CA1CA7CA14SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940019-B1 | SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND MEDICINAL USE THEREOF AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2018-03-28 | — | — | EP | disclosed |