SCHEMBL2000640

SCHEMBL2000640

COC(=O)C1CCCCC1(C=O)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 2/20 0.35
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
HTT P42858 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27207556 0.75 MAPT (0.41) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL11284836 0.72 ATM (0.40) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL30841160 0.70 MAPT (0.36) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL7638980 0.70 MAPT (0.37) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL3642324 0.70 ATM (0.37) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL2839539 0.69 MAPT (0.38) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL11513807 0.67 NPSR1 (0.39) MAPTNPSR1
SCHEMBL7374672 0.67 SLC6A4 (0.31) MAPT
SCHEMBL9610 0.67 ATM (0.33) MAPTNPSR1L3MBTL1ATMCYP1A2
SCHEMBL14375557 0.66 ATM (0.41) L3MBTL1ATMCYP1A2CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960305-B2 a mixture of a phosphazenium compound such as tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride, transition metal halides and an organic halogen compound as an activator, used for addition homo/copolymerization; living polymers MITSUI CHEMICALS, INC. (JP) 2011-06-14 US disclosed
US-20080177014-A1 Polymerization Catalyst Composition and Process for Production of Polymer MITSUI CHEMICALS, INC. (JP) 2008-07-24 US disclosed
EP-1857471-A1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER Mitsui Chemicals, Inc. (JP) 2007-11-21 EP disclosed