SCHEMBL7374672

SCHEMBL7374672

COC1CCCCC1(C=O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547690 0.73 LMNA (0.30)
SCHEMBL9556556 0.71 SLC6A4 (0.32) SLC6A4SLC6A3MAPT
SCHEMBL8357700 0.71 KDM4E (0.32) MAPT
SCHEMBL8970744 0.71 SLC6A4 (0.32) SLC6A4SLC6A3MAPT
SCHEMBL547519 0.71 HTT (0.31)
SCHEMBL28760194 0.69
SCHEMBL8969379 0.67 POLA1 (0.37)
SCHEMBL2000640 0.67 MAPT (0.38) MAPT
SCHEMBL13799456 0.66 SLC6A4 (0.34) SLC6A4SLC6A3
SCHEMBL14289922 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690841-A4 SYNTHETIC MATRIX METALLOPROTEASE INHIBITORS AND USES THEREOF GLYCOMED INC (US) 1996-03-13 EP disclosed
EP-0690841-A1 SYNTHETIC MATRIX METALLOPROTEASE INHIBITORS AND USES THEREOF GLYCOMED INCORPORATED (US) 1996-01-10 EP disclosed
WO-1995019965-A1 SYNTHETIC MATRIX METALLOPROTEASE INHIBITORS AND USES THEREOF GLYCOMED INCORPORATED (US) 1995-07-27 WO disclosed