Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 18/20 | 0.57 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879246 | 0.84 | CRACR2A (0.57) | CRACR2AORAI1KDM4EALDH1A1HPGD | |
| SCHEMBL31293507 | 0.84 | CRACR2A (0.54) | CRACR2AORAI1KDM4EALDH1A1HPGD | |
| SCHEMBL1882360 | 0.82 | CRACR2A (0.46) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL1668293 | 0.82 | CRACR2A (0.55) | CRACR2AORAI1ALDH1A1 | |
| SCHEMBL20006307 | 0.81 | CRACR2A (0.66) | CRACR2AORAI1 | |
| SCHEMBL1880912 | 0.81 | CRACR2A (0.56) | CRACR2AORAI1KDM4EALDH1A1HPGD | |
| SCHEMBL1668011 | 0.80 | CRACR2A (0.70) | CRACR2AORAI1 | |
| SCHEMBL1882594 | 0.79 | CRACR2A (0.55) | CRACR2AORAI1ALDH1A1 | |
| SCHEMBL1671173 | 0.79 | CRACR2A (0.39) | CRACR2AALDH1A1 | |
| SCHEMBL14881344 | 0.78 | ALDH1A1 (0.42) | CRACR2AORAI1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299361-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | Rhizen Pharmaceuticals S.A. (CH) | 2018-03-28 | — | — | EP | disclosed |