SCHEMBL20006872

SCHEMBL20006872

CCCc1ccc(-c2cc(C)c(C#Cc3ccc(-c4ccc(-c5ccc(C)cc5F)cc4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.35
FFAR1 O14842 5/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FFAR4 Q5NUL3 3/20 0.32
RARA P10276 1/20 0.31
RARG P13631 1/20 0.31
GRM5 P41594 1/20 0.30
KDM1A O60341 1/20 0.30
DGAT1 O75907 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004823 0.96 RARB (0.32) RARBFFAR1FFAR4KDM1A
SCHEMBL20004824 0.89 KDM1A (0.35) FFAR1FFAR4GRM5KDM1A
SCHEMBL19999549 0.89 RARB (0.45) RARBTSHRHSD17B10RARARARG
SCHEMBL20006853 0.87 FFAR1 (0.40) RARBFFAR1TSHRHSD17B10RARA
SCHEMBL19999586 0.87 RARB (0.39) RARBTSHRHSD17B10RARARARG
SCHEMBL19999468 0.83 RARB (0.32) RARBFFAR1TSHRHSD17B10
SCHEMBL19999568 0.83 RARB (0.32) RARBGRM5
SCHEMBL19999465 0.83 TSHR (0.43) RARBTSHRHSD17B10RARARARG
SCHEMBL19999418 0.83 RARB (0.34) RARBFFAR1TSHRHSD17B10RARA
SCHEMBL20005209 0.83 MCHR1 (0.36) RARBRARAGRM5KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208249-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-02-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed