⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999422 | 0.91 | TDP1 (0.83) | — | |
| SCHEMBL4697448 | 0.91 | TDP1 (0.83) | — | |
| SCHEMBL7296555 | 0.90 | — | — | |
| SCHEMBL7296108 | 0.90 | TDP1 (0.82) | — | |
| SCHEMBL1050014 | 0.88 | TDP1 (0.78) | — | |
| SCHEMBL2285048 | 0.88 | TDP1 (0.78) | — | |
| SCHEMBL8596242 | 0.87 | TDP1 (0.76) | — | |
| SCHEMBL8596237 | 0.87 | TDP1 (0.76) | — | |
| SCHEMBL7350548 | 0.84 | TDP1 (0.72) | — | |
| SCHEMBL18028783 | 0.84 | TDP1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090104116-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2009-04-23 | — | — | US | claimed |
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | claimed |
| EP-1979342-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | Jerini AG (DE) | 2008-10-15 | — | — | EP | claimed |
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | claimed |
| WO-2007088041-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2007-08-09 | — | — | WO | claimed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | claimed |
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4655299-A1 | NEW COMPOUNDS FOR TREATING STAPHYLOCOCCUS INFECTIONS | Ab2 Therapeutics, S. L. (ES) | 2025-12-03 | — | — | EP | disclosed |
| EP-4171563-B1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-08-06 | — | — | EP | disclosed |
| US-20250092019-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-03-20 | — | — | US | disclosed |
| WO-2024156895-A1 | NEW COMPOUNDS FOR TREATING STAPHYLOCOCCUS INFECTIONS | ABAC Therapeutics, S.L. (ES) | 2024-08-02 | — | — | WO | disclosed |
| EP-4406952-A1 | NEW COMPOUNDS FOR TREATING STAPHYLOCOCCUS INFECTIONS | ABAC THERAPEUTICS, S.L. (ES) | 2024-07-31 | — | — | EP | disclosed |
| US-11884652-B2 | Tetrazole derivatives as TRPA1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-01-30 | — | — | US | disclosed |
| WO-2007088041-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2007-08-09 | — | — | WO | disclosed |
| US-20070179127-A1 | Sulfonamide compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
| US-20060241115-A1 | Compounds and methods of use | AMGEN INC. | 2006-10-26 | — | — | US | disclosed |
| EP-0389282-B1 | Xanthinederivatives, process for their preparation and their pharmaceutical use | SMITHKLINE BEECHAM PHARMA GMBH (DE) | 2002-02-20 | — | — | EP | disclosed |
| EP-0386683-A2 | Xanthine derivatives having bronchodilating activity, a process for the preparation thereof and pharmaceutical compositions containing them | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1990-09-12 | — | — | EP | disclosed |
| US-3984568-A | Fungicidal cyclopropyl substituted 2-cyanoacetamide derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-05 | — | — | US | disclosed |