Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596237 | 1.00 | TDP1 (0.76) | TDP1PLGPLATLMNAKMT2A | |
| SCHEMBL2000699 | 0.87 | — | — | |
| SCHEMBL483345 | 0.85 | TDP1 (0.53) | TDP1PLGPLATLMNAKMT2A | |
| SCHEMBL483347 | 0.85 | TDP1 (0.53) | TDP1PLGPLATLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11285176 | 0.83 | TDP1 (0.52) | TDP1PLGPLATLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11285151 | 0.83 | TDP1 (0.52) | TDP1PLGPLATLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7443981 | 0.83 | TDP1 (0.52) | TDP1PLGPLATLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5505595 | 0.83 | TDP1 (0.52) | TDP1PLGPLATLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL10894938 | 0.82 | TDP1 (0.50) | TDP1PLGPLATLMNAKMT2A | |
| SCHEMBL8601731 | 0.81 | PLG (0.57) | TDP1PLGPLATLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159455-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-10292955-B2 | Composition for external use preparation with improved transdermal permeability | HYUNDAI PHARM CO., LTD. (KR) | 2019-05-21 | — | — | US | disclosed |
| US-20160058723-A1 | COMPOSITION FOR EXTERNAL USE PREPARATION WITH IMPROVED TRANSDERMAL PERMEABILITY | HYUNDAI PHARM CO., LTD. (KR) | 2016-03-03 | — | — | US | disclosed |
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159455-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | PNMT, HNMT, NNMT | TDP1 1933/4885PLG 917/4885PLAT 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.