Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.45 |
| ▸ | CHRNG | P07510 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10305457 | 0.84 | PARP1 (0.59) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3169530 | 0.83 | PARP1 (0.68) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21232994 | 0.81 | PARP1 (0.55) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL14537019 | 0.81 | PARP1 (0.55) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| Ethylene SCHEMBL27342996 | 0.80 | PARP1 (0.59) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL23931574 | 0.79 | PARP1 (0.63) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL17187940 | 0.79 | PARP1 (0.63) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL54859 | 0.79 | PARP1 (0.63) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1196056 | 0.79 | PARP1 (0.69) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1361076 | 0.79 | PARP1 (0.52) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |