SCHEMBL54859

SCHEMBL54859

CC(=O)c1cccc(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.63
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
ALDH1A1 P00352 3/20 0.59
HPGD P15428 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPT P10636 2/20 0.59
MAOA P21397 3/20 0.58
MAOB P27338 3/20 0.58
KCNK3 O14649 2/20 0.53
KCNK9 Q9NPC2 2/20 0.53
HTT P42858 2/20 0.53
GAA P10253 1/20 0.53
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
KDM4E B2RXH2 1/20 0.52
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17187940 1.00 PARP1 (0.63) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL23931574 1.00 PARP1 (0.63) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
Ethylene SCHEMBL27342996 0.96 PARP1 (0.59) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL27759980 0.92 PARP1 (0.55) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2236074 0.92 KMT2A (0.61) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
Benzenethiol SCHEMBL27914242 0.87 KCNK3 (0.51) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
Acetophenone SCHEMBL28272280 0.87 KMT2A (0.56) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2154450 0.86 UNG (0.51) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL279656 0.83 ALDH1A1 (0.59) NPC1RAB9ASMN1; SMN2ALDH1A1MEN1
SCHEMBL10305457 0.83 PARP1 (0.59) PARP1NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
US-12145897-B2 Preparation of chiral primary amine from asymmetric reductive amination of simple ketone catalyzed by ruthenium-diphosphine catalyst SHENZHEN CATALYS TECHNOLOGY CO., LTD (CN) 2024-11-19 US claimed
CN-118791483-A 1H-pyrazolo [3,4-b ] pyridine derivative and preparation method and application thereof 郑州大学 2024-10-18 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-117534539-B Preparation method of 2- (3' -chloro-phenyl) -propylene-1-alcohol 河北凡克新材料有限公司 2024-06-11 CN claimed
CN-117802061-A Amine dehydrogenase mutant and application thereof 新加坡国立大学 2024-04-02 CN claimed
US-11926609-B1 6′-(3-chlorophenyl)-2′-ethoxy-3,4′-bipyridine-3′-carbonitrile as antimicrobial compounds King Faisal University (SA) 2024-03-12 US claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-117568821-A Electrochemical synthesis method of quinoxaline derivative 齐齐哈尔医学院 2024-02-20 CN claimed
WO-2007070818-A1 SIX-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-06-21 WO claimed
WO-2007070816-A2 THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-06-21 WO claimed
WO-2007070826-A1 ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-06-21 WO claimed
CN-1821212-A Synthetic method for dapoxetine MAYAO CHEMICAL TECHNOLOGY CO L (CN) 2006-08-23 CN claimed
CN-1403433-A Synthesis of m-chloroacetophenone from benzoyl chloride JIANGSU SILING DYE GROUP CORP (CN) 2003-03-19 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0381656-A1 Alcohol-soluble/water-insoluble oil-containing antifreeze FIRST BRANDS CORPORATION (US) 1990-08-08 EP claimed
US-4272586-A HAVING A BONDING LAYER OF A PHOTOCURED MIXTURE OF A POLYENE, A POLYTHIOL, A PHOTOINIATOR, AND A SILICON-CONTAINING ANCHORING AGENT; OPTICAL LENSES; CARS DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-06-09 US claimed