SCHEMBL20007325

SCHEMBL20007325

Bc1cc(-c2ccccc2-c2ccc(-c3cc(C)c(-c4ccccc4)cn3)cc2)cc(-c2ccccc2-c2ccc(-c3cc(C)c(-c4ccccc4)cn3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.49
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
RAB9A P51151 6/20 0.38
NPC1 O15118 6/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
PDGFRB P09619 1/20 0.38
KDR P35968 1/20 0.38
FLT3 P36888 1/20 0.38
DYRK1A Q13627 2/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.35
ESR2 Q92731 1/20 0.35
SQOR Q9Y6N5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563336 0.95 LDHA (0.45) LDHAENPP3ENPP1RAB9ANPC1
SCHEMBL21202787 0.93 LDHA (0.50) LDHAENPP3ENPP1RAB9ANPC1
SCHEMBL21202809 0.88 LDHA (0.54) LDHAENPP3ENPP1RAB9ANPC1
SCHEMBL19834632 0.86 LDHA (0.49) LDHAENPP3ENPP1RAB9ANPC1
SCHEMBL21202862 0.85 NPC1 (0.38) LDHARAB9ANPC1SMN1; SMN2DYRK1A
SCHEMBL18015476 0.85 LDHA (0.57) LDHARAB9ANPC1SMN1; SMN2PDGFRB
SCHEMBL117744 0.84 LDHA (0.64) LDHARAB9ANPC1SMN1; SMN2PDGFRB
SCHEMBL29604379 0.84 LDHA (0.64) LDHARAB9ANPC1SMN1; SMN2PDGFRB
SCHEMBL18015496 0.84 LDHA (0.48) LDHANPC1KDRKDM4E
SCHEMBL23956296 0.84 LDHA (0.50) LDHAENPP3ENPP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515925-B1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
WO-2018054798-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-29 WO disclosed