Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094074 | 0.64 | RAF1 (0.56) | RAF1 | |
| SCHEMBL14107706 | 0.62 | FEN1 (0.45) | RAF1ABL1IRAK4 | |
| SCHEMBL20008461 | 0.62 | PBRM1 (0.35) | RAF1ABL1 | |
| SCHEMBL16095004 | 0.61 | RAF1 (0.56) | RAF1 | |
| SCHEMBL25699202 | 0.61 | RAF1 (0.39) | RAF1ABL1IRAK4 | |
| SCHEMBL16094439 | 0.61 | RAF1 (0.57) | RAF1 | |
| SCHEMBL20008598 | 0.60 | ABL1 (0.33) | ABL1 | |
| SCHEMBL16095043 | 0.60 | RAF1 (0.58) | RAF1 | |
| SCHEMBL16094697 | 0.60 | RAF1 (0.58) | RAF1 | |
| SCHEMBL16094510 | 0.60 | RAF1 (0.56) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |