Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 3/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009217 | 0.67 | RAF1 (0.39) | RAF1BRAF | |
| SCHEMBL20009306 | 0.66 | RAF1 (0.36) | RAF1BRAF | |
| SCHEMBL20008527 | 0.65 | RAF1 (0.36) | RAF1BRAF | |
| SCHEMBL20009716 | 0.64 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL24713128 | 0.63 | CYP1A2 (0.36) | CYP1A2POLBRAF1BRAFPRKCI | |
| SCHEMBL20008367 | 0.63 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL21766418 | 0.61 | PRKCI (0.52) | CYP1A2POLBBRAFPRKCI | |
| SCHEMBL15880501 | 0.60 | PRKCI (0.62) | CYP1A2POLBPRKCI | |
| SCHEMBL20009609 | 0.60 | BTK (0.32) | BRAF | |
| SCHEMBL9444923 | 0.60 | CYP1A2 (0.61) | CYP1A2POLBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |