Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008545 | 0.92 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL20009081 | 0.87 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL20009098 | 0.78 | RAF1 (0.76) | RAF1BRAF | |
| SCHEMBL20008526 | 0.78 | RAF1 (0.70) | RAF1BRAF | |
| SCHEMBL19529219 | 0.77 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL20010379 | 0.75 | RAF1 (0.72) | RAF1BRAF | |
| SCHEMBL20008439 | 0.75 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL20008346 | 0.73 | BRAF (0.86) | RAF1BRAF | |
| SCHEMBL20010330 | 0.73 | RAF1 (0.64) | RAF1BRAF | |
| SCHEMBL16121361 | 0.71 | BRAF (1.00) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |