SCHEMBL2000848

SCHEMBL2000848

CC(C)(CO)C(O)C(=O)NCCC(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.52
KCNH2 Q12809 1/20 0.52
VNN1 O95497 13/20 0.50
ECE1 P42892 3/20 0.36
AURKA O14965 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantothenic Acid SCHEMBL14126323 1.00 PTGS1 (0.52) PTGS1KCNH2VNN1ECE1AURKA
SCHEMBL7763866 0.92 PTGS1 (0.52) PTGS1KCNH2VNN1AURKA
SCHEMBL4851665 0.88 PTGS1 (0.71) PTGS1KCNH2VNN1AURKA
SCHEMBL28165293 0.87 PTGS1 (0.56) PTGS1KCNH2VNN1AURKA
Pantothenic Acid, Racemic SCHEMBL5437 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1
Pantothenic Acid SCHEMBL21547 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1
Pantothenic Acid SCHEMBL29872649 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1
Pantothenic Acid SCHEMBL7016631 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1
Pantothenic Acid, Racemic SCHEMBL21114380 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1
Pantothenic Acid SCHEMBL14126322 0.87 PTGS1 (0.67) PTGS1KCNH2VNN1ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964234-B2 High mineral content dietary supplement NEWAYS, INC. (US) 2011-06-21 US disclosed
EP-1322751-A2 GLUTARYL CEPHALOSPORIN AMIDASE FROM PSEUDOMONAS DIMINUTA BS-203 Bristol-Myers Squibb Company (US) 2003-07-02 EP disclosed
EP-1091738-A4 BICYCLIC sPLA 2 INHIBITORS LILLY CO ELI (US) 2003-03-05 EP disclosed
WO-2002024879-A2 GLUTARYL CEPHALOSPORIN AMIDASE FROM PSEUDOMONAS DIMINUTA BS-203 BRISTOL-MYERS SQUIBB COMPANY (US) 2002-03-28 WO disclosed
EP-1091738-A1 BICYCLIC sPLA 2 INHIBITORS ELI LILLY AND COMPANY (US) 2001-04-18 EP disclosed
WO-2000000201-A1 BICYCLIC sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 2000-01-06 WO disclosed