Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | VNN1 | O95497 | 13/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616729 | 0.88 | PTGS1 (0.59) | PTGS1KCNH2VNN1ZDHHC20MEN1 | |
| SCHEMBL2000848 | 0.87 | PTGS1 (0.52) | PTGS1KCNH2VNN1AURKA | |
| Pantothenic Acid SCHEMBL14126323 | 0.87 | PTGS1 (0.52) | PTGS1KCNH2VNN1AURKA | |
| SCHEMBL7763866 | 0.87 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20AURKA | |
| SCHEMBL2009906 | 0.87 | PTGS1 (0.58) | PTGS1KCNH2VNN1 | |
| SCHEMBL2009904 | 0.87 | PTGS1 (0.58) | PTGS1KCNH2VNN1 | |
| SCHEMBL4851665 | 0.86 | PTGS1 (0.71) | PTGS1KCNH2VNN1ZDHHC20AURKA | |
| Ammonia Solution, Strong SCHEMBL27681737 | 0.85 | PTGS1 (0.56) | PTGS1KCNH2VNN1 | |
| SCHEMBL7524756 | 0.84 | PTGS1 (0.63) | PTGS1KCNH2VNN1 | |
| SCHEMBL7524751 | 0.84 | PTGS1 (0.63) | PTGS1KCNH2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108420819-A | New compositions for treating neurological disorder | 法耐斯特公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-108057033-A | For treating the new compositions of amyotrophic lateral sclerosis | 法耐斯特公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-104487064-B | Novel compositions for the treatment of amyotrophic lateral sclerosis | 法耐斯特公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107106521-A | New treatment for treating Parkinson's | 法耐斯特公司 | 2017-08-29 | — | — | CN | disclosed |