Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | LTA4H | P09960 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20942365 | 0.92 | RNF4 (0.71) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20941574 | 0.92 | MEN1 (0.68) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20941569 | 0.92 | RNF4 (0.67) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20942366 | 0.92 | RNF4 (0.67) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL23323205 | 0.92 | POLB (0.68) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20942364 | 0.87 | KMT2A (0.68) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20941788 | 0.87 | FNTA (0.67) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL20941792 | 0.87 | RNF4 (0.71) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL2173035 | 0.87 | MTNR1A (0.73) | RNF4ALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL3382618 | 0.87 | RNF4 (1.00) | RNF4ALDH1A1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964625-B2 | Antibiotics comprising bis(1-aryl-5-tetrazoly1)methane derivatives | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2011-06-21 | — | — | US | disclosed |
| EP-1937257-B1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | TNO (NL) | 2010-12-08 | — | — | EP | disclosed |
| US-20080280964-A1 | Novel Antibiotics Comprising Bis(1-Aryl-5-Tetrazolyl)Methane Derivatives | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280964-A1 | Novel Antibiotics Comprising Bis(1-Aryl-5-Tetrazolyl)Methane Derivatives | LAS1L, AAAS, RPS5 | RNF4 693/4885ALDH1A1 3743/4885MEN1 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.