Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008248 | 0.79 | KMO (0.37) | RAF1BRAF | |
| SCHEMBL20008238 | 0.77 | KMO (0.37) | RAF1BRAF | |
| SCHEMBL20009642 | 0.73 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL20009647 | 0.69 | BRAF (0.47) | RAF1BRAF | |
| SCHEMBL19529245 | 0.69 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL20009446 | 0.68 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL20008513 | 0.66 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL20008794 | 0.66 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL20008332 | 0.65 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL16103173 | 0.65 | RAF1 (1.00) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |