Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021192 | 0.88 | CA12 (0.42) | CA12CA2CA9CA1TSHR | |
| SCHEMBL27977920 | 0.86 | ABCB11 (0.31) | CA12CA2CA9CA1 | |
| SCHEMBL8881781 | 0.75 | — | — | |
| SCHEMBL9113596 | 0.74 | CA12 (0.41) | CA12CA2CA9CA1TSHR | |
| SCHEMBL19446930 | 0.74 | — | — | |
| SCHEMBL610309 | 0.72 | CA12 (0.40) | CA12CA2CA9CA1TSHR | |
| SCHEMBL24244881 | 0.71 | CA12 (0.32) | CA12CA2CA9CA1 | |
| SCHEMBL12512753 | 0.70 | KMT2A (0.41) | TSHR | |
| SCHEMBL25912898 | 0.70 | — | — | |
| SCHEMBL22872172 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |