Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30282824 | 0.78 | BPTF (0.51) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL195203 | 0.78 | BPTF (0.51) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL22959766 | 0.76 | SMARCA2 (0.54) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL195335 | 0.76 | BPTF (0.49) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL31065028 | 0.76 | SMARCA2 (0.54) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL195388 | 0.75 | BPTF (0.45) | BPTFADRB1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL23037272 | 0.74 | SMARCA2 (0.52) | BPTFADRB1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL23037230 | 0.74 | BPTF (0.47) | BPTFADRB1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL516604 | 0.74 | BPTF (0.44) | BPTFADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL28846377 | 0.73 | HTR3A (0.36) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |