Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644379 | 0.61 | P2RX7 (0.56) | HCRTR1HCRTR2P2RX7ATM | |
| SCHEMBL29206844 | 0.61 | P2RX7 (0.43) | HCRTR1HCRTR2P2RX7 | |
| SCHEMBL30876162 | 0.61 | P2RX7 (0.43) | HCRTR1HCRTR2P2RX7 | |
| SCHEMBL10240443 | 0.60 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL30614424 | 0.59 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL29079317 | 0.59 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL20009697 | 0.58 | — | — | |
| SCHEMBL7519054 | 0.57 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL17210751 | 0.57 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL12459518 | 0.56 | P2RX7 (0.45) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |