Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009437 | 0.84 | RAF1 (0.38) | RAF1BRAF | |
| SCHEMBL26815928 | 0.68 | RAF1 (0.66) | RAF1BRAF | |
| SCHEMBL20009420 | 0.65 | RAF1 (0.32) | RAF1BRAF | |
| SCHEMBL20009106 | 0.64 | MAPT (0.35) | RAF1 | |
| SCHEMBL20009442 | 0.64 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL20009398 | 0.61 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL20008439 | 0.58 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL20010375 | 0.58 | RAF1 (0.52) | RAF1BRAF | |
| SCHEMBL20008454 | 0.56 | NPC1 (0.31) | — | |
| SCHEMBL23654343 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |