Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | RAF1 | P04049 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009437 | 0.73 | RAF1 (0.38) | RAF1 | |
| SCHEMBL20009433 | 0.64 | RAF1 (0.37) | RAF1 | |
| SCHEMBL26923382 | 0.64 | DYRK1A (0.43) | ABL1KMT2A | |
| SCHEMBL20008468 | 0.59 | RAF1 (0.43) | RAF1 | |
| SCHEMBL26923056 | 0.59 | HTR2C (0.41) | ABL1RAF1KMT2A | |
| SCHEMBL23654969 | 0.58 | BRAF (0.33) | ABL1 | |
| SCHEMBL26949253 | 0.56 | KDM4E (0.44) | ABL1KMT2A | |
| SCHEMBL31734596 | 0.56 | KDM4E (0.44) | ABL1KMT2A | |
| SCHEMBL26923369 | 0.55 | ABL1 (0.55) | ABL1 | |
| SCHEMBL26948394 | 0.54 | PARP10 (0.43) | MAPTABL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |