Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 11/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.44 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17746971 | 0.89 | NOD1 (0.49) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL17746969 | 0.89 | NOD1 (0.49) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL17746979 | 0.89 | NOD1 (0.49) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL17746981 | 0.89 | NOD1 (0.49) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL26113216 | 0.89 | NOD1 (0.49) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL31411843 | 0.87 | FOLH1 (0.53) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL20009714 | 0.86 | NOD1 (0.48) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL25482404 | 0.82 | NOD1 (0.51) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL25482477 | 0.81 | NOD1 (0.54) | GNPATFOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL17746989 | 0.81 | NOD1 (0.65) | NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358988-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200216498-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-09 | — | — | US | disclosed |
| US-10633419-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633419-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | GNPAT 2839/4885FOLH1 550/4885NAALAD2 617/4885 |
| US-11358988-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | GNPAT 2839/4885FOLH1 550/4885NAALAD2 617/4885 |
| US-20180086793-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | GNPAT 2839/4885FOLH1 550/4885NAALAD2 617/4885 |
| US-20200216498-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | GNPAT 2839/4885FOLH1 550/4885NAALAD2 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.