SCHEMBL20009831

SCHEMBL20009831

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4-c4ccc(-n5c6ccccc6c6ccc7ccccc7c65)cc4)cc3)c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ F2 P00734 1/20 0.32
▸ F10 P00742 1/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ PER2 O15055 1/20 0.31
▸ CRY1 Q16526 1/20 0.31
▸ CRY2 Q49AN0 1/20 0.31
▸ HDAC4 P56524 1/20 0.31
▸ PDE6D O43924 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24374024 0.96 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL24374278 0.96 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL20009818 0.94 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4PDE6D
SCHEMBL20812940 0.94 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4PDE6D
SCHEMBL24374251 0.93 KDM4E (0.35) KDM4EATML3MBTL1F2F10
SCHEMBL24949615 0.93 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PDE6D
SCHEMBL20009830 0.93 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PDE6D
SCHEMBL15138069 0.93 KDM4E (0.36) KDM4EATML3MBTL1F2F10
SCHEMBL24948574 0.93 KDM4E (0.31) KDM4EATML3MBTL1F2F10
SCHEMBL26165988 0.93 CA12 (0.31) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573824-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2020-02-25 — — US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 — — US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, BMI1 KDM4E 390/4885ATM 2315/4885L3MBTL1 1563/4885
US-10573824-B2 Compound and organic electronic element comprising same OR10J3, ETV6, BMI1 KDM4E 390/4885ATM 2315/4885L3MBTL1 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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