Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709837 | 0.85 | ALDH1A1 (0.83) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL20705655 | 0.84 | POLB (0.75) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL5862372 | 0.84 | POLB (0.75) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL19425502 | 0.84 | POLB (0.75) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL20013749 | 0.84 | MEN1 (1.00) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL15702626 | 0.83 | POLB (0.78) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL7821727 | 0.82 | POLB (0.68) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL22142539 | 0.79 | MEN1 (0.65) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL20010005 | 0.79 | POLB (0.64) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL7829160 | 0.78 | MEN1 (0.73) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086696-A1 | RUNX2 Transcription Factor Inhibitors and Uses Thereof | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086696-A1 | RUNX2 Transcription Factor Inhibitors and Uses Thereof | CBFB, RUNX1, NCOA3 | ALDH1A1 4181/4885KDM4E 983/4885MEN1 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.