Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | AHCY | P23526 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | AMD1 | P17707 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20010148 | 0.91 | ADORA2A (0.42) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL14946120 | 0.80 | ADORA2A (0.46) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL14929097 | 0.80 | ADORA2A (0.46) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL20009991 | 0.80 | ADORA2A (0.42) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL20010089 | 0.77 | ADORA2A (0.47) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL15723511 | 0.77 | ADORA2A (0.47) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL20010244 | 0.77 | HPGD (0.39) | — | |
| SCHEMBL20010217 | 0.76 | ADORA2A (0.46) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL20010221 | 0.76 | ADORA2A (0.46) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL20010091 | 0.76 | ADORA2A (0.46) | ADORA2AADORA2BAHCYDNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086807-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE | MODERNATX, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086807-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE | POLRMT, POLM, POLN | ADORA2A 3329/4885ADORA2B 3118/4885AHCY 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.