Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701389 | 0.81 | P2RX7 (0.56) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL253582 | 0.81 | P2RX7 (0.56) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL4857793 | 0.79 | P2RX7 (0.58) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL12381903 | 0.79 | P2RX7 (0.58) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL15181878 | 0.79 | P2RX7 (0.53) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL662074 | 0.79 | P2RX7 (0.53) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL15181812 | 0.79 | P2RX7 (0.53) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL31116010 | 0.78 | P2RX7 (0.49) | P2RX7MAPK1 | |
| SCHEMBL23873562 | 0.77 | P2RX7 (0.51) | P2RX7MAPK1 | |
| SCHEMBL4859383 | 0.77 | P2RX7 (0.56) | P2RX7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054365-A1 | NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BEIGENE, LTD. (KY) | 2018-03-29 | — | — | WO | disclosed |