Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 11/20 | 0.43 |
| ▸ | DRD3 | P35462 | 11/20 | 0.43 |
| ▸ | DRD4 | P21917 | 9/20 | 0.43 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24611645 | 0.72 | — | — | |
| SCHEMBL24611659 | 0.69 | — | — | |
| SCHEMBL18256023 | 0.67 | HTR2A (0.52) | SMN1; SMN2HTR2ALMNACYP1A2 | |
| SCHEMBL9641726 | 0.66 | SMN1; SMN2 (0.70) | SMN1; SMN2ALOX15HTTDRD2DRD3 | |
| SCHEMBL24611657 | 0.66 | — | — | |
| SCHEMBL27509034 | 0.65 | SMN1; SMN2 (0.68) | SMN1; SMN2ALOX15HTTDRD2DRD3 | |
| SCHEMBL24611651 | 0.65 | MEN1 (0.30) | SMN1; SMN2 | |
| SCHEMBL8422776 | 0.64 | DRD2 (0.57) | SMN1; SMN2ALOX15HTTDRD2DRD3 | |
| SCHEMBL20358330 | 0.64 | SMN1; SMN2 (0.62) | SMN1; SMN2ALOX15HTTDRD2DRD3 | |
| SCHEMBL14835424 | 0.64 | SMN1; SMN2 (0.67) | SMN1; SMN2ALOX15HTTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |