Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.50 |
| ▸ | BUB1 | O43683 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995629 | 0.91 | MAPK14 (0.48) | MAPK14GSK3BDYRK1APRKD1MAPK13 | |
| SCHEMBL1996314 | 0.84 | MAPK14 (0.51) | MAPK14GSK3BDYRK1APRKD1MAPK13 | |
| SCHEMBL1998794 | 0.83 | MAPK14 (0.54) | MAPK14GSK3BPRKD1MAPK13MAPK12 | |
| SCHEMBL1996259 | 0.82 | MAPK14 (0.53) | MAPK14BUB1GSK3BPRKD1MAPK13 | |
| SCHEMBL1999853 | 0.82 | MAPK14 (0.53) | MAPK14BUB1PRKD1MAPK13MAPK12 | |
| SCHEMBL1997675 | 0.81 | MAPK14 (0.52) | MAPK14GSK3BPRKD1MAPK13MAPK12 | |
| SCHEMBL1995900 | 0.81 | TGFBR1 (0.60) | MAPK14BUB1GSK3BPRKD1MAPK13 | |
| Hydrochloric Acid SCHEMBL6640025 | 0.80 | TGFBR1 (0.59) | MAPK14BUB1GSK3BPRKD1MAPK13 | |
| SCHEMBL25204815 | 0.79 | MAPK14 (0.56) | MAPK14BUB1GSK3BMAPK13MAPK12 | |
| SCHEMBL30387946 | 0.79 | MAPK14 (0.56) | MAPK14BUB1GSK3BMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |