Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282537 | 0.83 | CYP1A2 (0.48) | CYP1A2ALDH1A1ADRA2AKAT2B | |
| SCHEMBL13997585 | 0.82 | CYP1A2 (0.44) | CYP1A2ALDH1A1ADRA2AHRH4KAT2B | |
| SCHEMBL9035633 | 0.80 | CYP1A2 (0.50) | CYP1A2ADRA2AKMT2A | |
| SCHEMBL14509674 | 0.79 | GNAI3 (0.49) | ALDH1A1SIGMAR1 | |
| SCHEMBL21638039 | 0.78 | GNAI3 (0.41) | CYP1A2ALDH1A1ADRA2AHRH4 | |
| SCHEMBL10229134 | 0.77 | CYP1A2 (0.41) | CYP1A2ALDH1A1KAT2B | |
| SCHEMBL25689653 | 0.77 | CYP1A2 (0.55) | CYP1A2ALDH1A1ADRA2AKAT2B | |
| SCHEMBL2885311 | 0.75 | CYP1A2 (0.52) | CYP1A2ALDH1A1ADRA2AKAT2B | |
| SCHEMBL17888194 | 0.75 | CYP1A2 (0.52) | CYP1A2ALDH1A1ADRA2AKAT2B | |
| SCHEMBL22479354 | 0.75 | KDM4E (0.37) | CYP1A2ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152204-B1 | CARBAMATE DERIVATIVES WHICH ARE BOTH PHOSPHODIESTERASE 4 (PDE4) ENZYME INHIBITORS AND MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-03-28 | — | — | EP | disclosed |