Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986085 | 0.86 | RARB (0.38) | RARBMCL1NPC1RAB9ALPL | |
| SCHEMBL17614863 | 0.86 | RARB (0.38) | RARBMCL1NPC1RAB9ALPL | |
| SCHEMBL16377223 | 0.85 | CTSL (0.41) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL18779777 | 0.85 | CTSL (0.41) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL16186381 | 0.85 | AKR1C3 (0.46) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL12172447 | 0.84 | RARB (0.38) | RARBMCL1NPC1RAB9ATP53 | |
| SCHEMBL16377234 | 0.84 | RARB (0.47) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL20013004 | 0.84 | MCL1 (0.50) | RARBRARARARGMCL1LPL | |
| SCHEMBL712607 | 0.84 | RARB (0.40) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL16377221 | 0.84 | RARB (0.43) | RARBRARARARGMCL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526308-B1 | LIQUID-CRYSTALLINE MEDIUM, LIQUID CRYSTAL COMPOUND AND LIQUID-CRYSTAL DISPLAY DEVICE COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |
| US-10883047-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-01-05 | — | — | US | disclosed |
| WO-2018073151-A1 | LIQUID-CRYSTALLINE MEDIUM, LIQUID CRYSTAL COMPOUND AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2018-04-26 | — | — | WO | disclosed |
| US-20180086980-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| EP-3299438-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2018-03-28 | — | — | EP | disclosed |