Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uridine Triacetate SCHEMBL19308912 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL871011 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL16455208 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL12928917 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL14950624 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL15279673 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL12900042 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL19308849 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL10350038 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 | |
| Uridine Triacetate SCHEMBL7924235 | 0.88 | LMNA (0.64) | LMNATHRBSMN1; SMN2HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018058148-A1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2018-03-29 | — | — | WO | disclosed |