Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 12/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995159 | 0.99 | ADORA2B (0.45) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL20014416 | 0.97 | ADORA2B (0.45) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL20014196 | 0.96 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014251 | 0.92 | ADORA2B (0.52) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL20015114 | 0.91 | ADORA2B (0.53) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL19995197 | 0.90 | ADORA2B (0.44) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014237 | 0.90 | ADORA2B (0.53) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL20014687 | 0.89 | ADORA2B (0.43) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014420 | 0.89 | ADORA2B (0.45) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19994300 | 0.89 | ADORA2B (0.42) | ADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |