Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799433 | 0.79 | ADORA2B (0.45) | ADORA2BTP53ERCC5FEN1ALDH1A1 | |
| SCHEMBL19994419 | 0.76 | — | — | |
| SCHEMBL19994036 | 0.75 | ADORA2A (0.52) | ADORA2BPOLB | |
| SCHEMBL19995106 | 0.73 | ADORA2A (0.52) | ADORA2B | |
| SCHEMBL19995199 | 0.71 | MAPT (0.39) | TP53ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL19995255 | 0.71 | ADORA2B (0.36) | ADORA2B | |
| SCHEMBL19994338 | 0.67 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL20014394 | 0.67 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL19994177 | 0.67 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL19995188 | 0.67 | ADORA2B (0.35) | ADORA2BHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |