SCHEMBL20014990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20015142	0.90	F12 (0.50)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL21183650	0.89	F12 (0.52)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL20015371	0.85	F12 (0.50)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL29475107	0.85	F12 (0.50)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL21175127	0.85	F12 (0.35)	F12C5AR1
	SCHEMBL31692418	0.84	F12 (0.45)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL21725722	0.81	C5AR1 (0.67)	F12C5AR1ESR2NR1H2ADORA1
	SCHEMBL20014993	0.81	C5AR1 (0.41)	F12C5AR1ESR2NR1H2MAPT
	SCHEMBL31424521	0.80	C5AR1 (0.45)	F12C5AR1NR1H2
	SCHEMBL20015355	0.78	NR1H2 (0.33)	F12C5AR1ESR2NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.