Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 15/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183596 | 0.90 | C5AR1 (0.41) | GLP1R | |
| SCHEMBL21175426 | 0.89 | GLP1R (0.35) | GLP1R | |
| SCHEMBL31692183 | 0.85 | C5AR1 (0.38) | — | |
| SCHEMBL20015372 | 0.81 | C5AR1 (0.42) | — | |
| SCHEMBL30178446 | 0.81 | C5AR1 (0.42) | — | |
| SCHEMBL20014993 | 0.81 | C5AR1 (0.41) | GLP1R | |
| SCHEMBL21175380 | 0.80 | DPP4 (0.39) | GLP1R | |
| SCHEMBL21175207 | 0.80 | GLP1R (0.35) | GLP1R | |
| SCHEMBL20015363 | 0.79 | C5AR1 (0.41) | — | |
| SCHEMBL21175302 | 0.78 | GLP1R (0.33) | SMN1; SMN2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018056453-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | 中外製薬株式会社 | 2018-03-29 | — | — | WO | disclosed |