SCHEMBL30178446

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20015372	1.00	C5AR1 (0.42)	C5AR1F12HPGDSDPP4DPP8
	SCHEMBL31692488	0.96	C5AR1 (0.39)	C5AR1F12HPGDSTHRBTP53
	SCHEMBL21183596	0.92	C5AR1 (0.41)	C5AR1F12HPGDSTHRBESR2
	SCHEMBL20014993	0.88	C5AR1 (0.41)	C5AR1F12HPGDSTP53ESR2
	SCHEMBL21175380	0.88	DPP4 (0.39)	DPP4DPP8DPP9DPP7
	SCHEMBL31692183	0.87	C5AR1 (0.38)	C5AR1F12HPGDSTHRBTP53
	SCHEMBL20015363	0.87	C5AR1 (0.41)	C5AR1F12HPGDSTHRBESR2
	SCHEMBL22750895	0.83	C5AR1 (0.32)	C5AR1DPP4DPP8DPP9DPP7
	SCHEMBL20015371	0.82	F12 (0.50)	C5AR1F12HPGDSDPP4DPP8
	SCHEMBL29475107	0.82	F12 (0.50)	C5AR1F12HPGDSDPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.