Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280681 | 0.98 | SMPD3 (0.68) | SMPD3 | |
| SCHEMBL18850559 | 0.86 | SMPD3 (0.52) | SMPD3 | |
| SCHEMBL23518736 | 0.86 | SMPD3 (0.64) | SMPD3 | |
| SCHEMBL31259868 | 0.81 | SMPD3 (1.00) | SMPD3 | |
| SCHEMBL31259862 | 0.81 | SMPD3 (1.00) | SMPD3 | |
| SCHEMBL15989384 | 0.79 | SMPD3 (0.68) | SMPD3 | |
| SCHEMBL18968044 | 0.79 | SMPD3 (1.00) | SMPD3 | |
| SCHEMBL24689691 | 0.79 | SMPD3 (0.68) | SMPD3 | |
| SCHEMBL31259884 | 0.79 | SMPD3 (1.00) | SMPD3 | |
| SCHEMBL20016005 | 0.79 | SMPD3 (0.62) | SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299372-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OFSUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2018-03-28 | — | — | EP | disclosed |