Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324695 | 0.92 | ALDH1A1 (0.55) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324705 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18325013 | 0.78 | KDM4E (0.53) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324980 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324710 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324702 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324679 | 0.72 | KDM4E (0.64) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324897 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL18324801 | 0.71 | KDM4E (0.61) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL25252905 | 0.71 | TSHR (0.54) | ALDH1A1KDM4EBRD4POLBCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931347-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (US) | 2018-04-03 | — | — | US | disclosed |