⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24119914 | 0.83 | NOD1 (0.35) | — | |
| SCHEMBL23790945 | 0.80 | NOD1 (0.31) | — | |
| SCHEMBL24119971 | 0.80 | NOD1 (0.35) | — | |
| SCHEMBL21902130 | 0.78 | NOD1 (0.34) | — | |
| SCHEMBL22857315 | 0.76 | NOD1 (0.41) | — | |
| SCHEMBL16248525 | 0.75 | NOD1 (0.36) | — | |
| SCHEMBL16248526 | 0.75 | NOD1 (0.36) | — | |
| SCHEMBL24119913 | 0.74 | NOD1 (0.35) | — | |
| SCHEMBL19871861 | 0.73 | NOD1 (0.37) | — | |
| SCHEMBL23136493 | 0.72 | NOD1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932581-B2 | Compositions and methods for modulating apolipoprotein C-III expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-03 | — | — | US | disclosed |