Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016709 | 0.81 | HRH3 (0.39) | QPCTHTR2AHTR2CKDRBCHE | |
| SCHEMBL20016704 | 0.79 | EPHX2 (0.70) | EPHX2HTR2AHTR2CKDR | |
| SCHEMBL2683503 | 0.77 | EPHX2 (0.59) | EPHX2HTR2AHTR2CKDRBRAF | |
| SCHEMBL22125326 | 0.75 | HTR2A (0.59) | EPHX2QPCTHTR2AHTR2CBRAF | |
| SCHEMBL2682353 | 0.75 | EPHX2 (0.64) | EPHX2HTR2AHTR2CBRAFMAPK14 | |
| SCHEMBL2681361 | 0.73 | BRAF (0.77) | EPHX2HTR2AHTR2CKDRBRAF | |
| SCHEMBL14621614 | 0.72 | POLB (0.56) | BCHEACHEKDM4EMAPTALOX15 | |
| SCHEMBL12463246 | 0.70 | MTOR (0.54) | — | |
| SCHEMBL14937415 | 0.67 | TSHR (0.62) | EPHX2HTR2AHTR2CKDRBRAF | |
| SCHEMBL10220711 | 0.66 | HTR2A (0.56) | EPHX2QPCTHTR2AHTR2CKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932300-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-03 | — | — | US | disclosed |