Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463249 | 0.83 | MTOR (0.73) | MTOR | |
| SCHEMBL12463124 | 0.81 | MTOR (0.74) | MTOR | |
| SCHEMBL12463247 | 0.78 | MTOR (0.50) | MTOR | |
| SCHEMBL12463245 | 0.77 | MTOR (0.53) | MTOR | |
| SCHEMBL12463001 | 0.75 | MTOR (0.55) | MTOR | |
| SCHEMBL13718467 | 0.71 | MTOR (1.00) | MTOR | |
| SCHEMBL13718871 | 0.70 | MTOR (1.00) | MTOR | |
| SCHEMBL12463253 | 0.70 | MTOR (0.42) | MTOR | |
| SCHEMBL20016705 | 0.70 | EPHX2 (0.46) | — | |
| SCHEMBL12463043 | 0.70 | MTOR (0.70) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080568-A2 | NOVEL PYRIMIDINE COMPOUNDS AS MTOR AND P13K INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2011-07-07 | — | — | WO | disclosed |