Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23897518 | 0.80 | SRC (0.34) | ADKSRCCA12CA1CA2 | |
| SCHEMBL868823 | 0.74 | ADK (0.49) | ADKSRCCA12CA1CA2 | |
| SCHEMBL30582615 | 0.70 | ADK (0.43) | ADKSRCCA12CA1CA2 | |
| SCHEMBL25612067 | 0.70 | ADK (0.46) | ADKSRCMEN1NR2F2KMT2A | |
| SCHEMBL26107666 | 0.70 | ADK (0.43) | ADKSRCCA12CA1CA2 | |
| SCHEMBL1939924 | 0.70 | ADK (0.46) | ADKSRCMEN1NR2F2KMT2A | |
| SCHEMBL18640950 | 0.69 | ADK (0.54) | ADKSRC | |
| SCHEMBL24843653 | 0.69 | — | — | |
| SCHEMBL4079517 | 0.68 | ADK (0.44) | ADKSRCMEN1NR2F2KMT2A | |
| SCHEMBL29052179 | 0.68 | ADK (0.41) | ADKSRCCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932346-B2 | Pyrrolopyrimidines for use in influenza virus infection | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-03 | — | — | US | disclosed |