SCHEMBL20018409

SCHEMBL20018409

CCCCCCCCCNC(=O)CC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.64
RIMKLA Q8IXN7 1/20 0.58
NAALAD2 Q9Y3Q0 1/20 0.58
NOD1 Q9Y239 4/20 0.57
GLP1R P43220 8/20 0.54
CASP2 P42575 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16374702 1.00 FOLH1 (0.64) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL22536141 0.99 FOLH1 (0.66) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL12836737 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL22237179 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL20018407 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL15003787 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL21417883 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL18030076 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL20018413 0.93 FOLH1 (0.67) FOLH1RIMKLANAALAD2NOD1GLP1R
SCHEMBL18059393 0.92 FOLH1 (0.69) FOLH1RIMKLANAALAD2NOD1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3545978-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2021-09-08 EP disclosed
EP-3545978-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2019-10-02 EP disclosed
EP-3300746-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2019-05-15 EP disclosed
EP-3300746-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2018-04-04 EP disclosed